Transparency or Proper Study Valuation Procedures Missed?

نویسندگان

  • Giampiero Favato
  • Gianluca Baio
  • Alessandro Capone
  • Andrea Marcellusi
  • Silvano Costa
  • Giorgia Garganese
  • Mauro Picardo
  • Mike Drummond
  • Bengt Jonsson
  • Giovanni Scambia
  • Peter Zweifel
  • Francesco S. Mennini
چکیده

To the Editor: We refer to a recently published article that shows a new Bayesian method, applied to assess a vaccination strategy preventing human papillomavirus (HPV)-related diseases. The article basically describes a model for the economic evaluation of the quadrivalent HPV vaccine in Italy, concluding that it is a costeffective strategy. Although any model, Bayesian or Frequentist, should be “populated” with reliable data, we felt some concern about many “inputs” regarding the Italian setting that could weaken the authors’ conclusions. We have listed some of the main ones. Real data on Italian vaccination coverage are referenced by an abstract, without specifying that this refers to a very small region in Italy (Basilicata, 0.97% of the whole Italian population). Thereafter, table 1 refers for vaccination compliance and coverage to another article, published in Italian, focussed on the efficacy of the quadrivalent vaccine. Data on health states associated with HPV-related diseases refer to another abstract, then unspecified Italian utility weights for health states were applied, but to our knowledge, no utility tariffs have been validated so far in Italy. Utilities of cervical cancer, genital and cervical lesions, all refer to an article on the costs of varicellarelated hospitalizations in table 1. The vaccine price is not consistent with published data, and we could not find the figure used as a mean (h69.13, see table 1) in the references. More in general, the authors state that the cost-effectiveness of the quadrivalent vaccine is proven, ignoring the other, bivalent vaccine against HPV. As 3 recent critical reviews on economic evaluations regarding HPV vaccines—not cited in the article— concluded that long-term models on HPV vaccination lack transparency in key assumptions and methodological choices, we wonder whether the results of this model (producing a “virtual” follow-up of 90 y) can really be considered more reliable than the others already published.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

تعیین رابطه بین شفافیت اطلاعاتی، نقد شوندگی و ارزشیابی شرکت‌

در این مقاله به تعیین رابطه بین شفافیت اطلاعاتی، نقد شوندگی و ارزش شرکت شرکت‌های پذیرفته شده در بورس اوراق بهادار تهران پرداخته شده است. این تحقیق از نوع توصیفی-همبستگی بوده و روش شناسی تحقیق از نوع پس رویدادی و نوعی تحقیق کاربردی است. برای آزمون فرضیه تحقیق از مدل رگرسونی معمولی با استفاده از داده‌های تلفیقی بهره گرفته شده است. فرض اصلی تحقیق آن است که افزایش شفافیت اطلاعاتی منجر به افزایش سطح...

متن کامل

Impact of Economic Transparency on Economic Growth in the Middle East countries

Economic transparency will lead to economic stability and corruption decline. Thus the shortage of transparency mechanisms, laws and procedures will raise corruption and make it tough to cutout corruption. Also, loss of transparency in financial and economic system creates to instability, inappropriate allocation of resources, the boom of injustice and inequality and as a result paves the way f...

متن کامل

Missed nursing care and its related factors from the points of view of nurses affiliated to Kerman University of Medical Sciences in 2017

Background & Aim: Nursing care is an essential part of health care services. Missed nursing care is a new concept referring to any aspect of care, that is omitted or delayed. The present study aimed to assess missed nursing care and its related factors from the viewpoints of nurses working in the hospitals affiliated to Kerman University of Medical Sciences in 2017. Methods & Materials: In thi...

متن کامل

Early dental treatments for patients with cleidocranial dysplasia.

OBJECTIVE To explore the early dental interventional strategies for adolescent patients and a child patient with cleidocranial dysplasia (CCD). METHODS Surgical exposure using the apically repositioned flap technique combined with orthodontic traction was used in the adolescent patients whose ideal treatment time for initiating treatment was missed. For the child patient whose ideal treatment...

متن کامل

Developing a Paradigm for Fair Valuation in Tehran Stock Exchange

The concept of value is of great importance for investors. The goal of different groups of investors is always to maximize the value of their capital. The aim of this research is developing factors effective on securities in capital market in order to develop a paradigm for fair valuation that leads investors to make better decisions. To study fair value in a precise and comprehensive way, effe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 51  شماره 

صفحات  -

تاریخ انتشار 2013